Peak oxygen uptake and mortality in children with cystic fibrosis
نویسندگان
چکیده
منابع مشابه
Peak oxygen uptake and mortality in children with cystic fibrosis.
BACKGROUND Single measurements of peak oxygen uptake (VO2) have been shown to predict mortality in patients with cystic fibrosis (CF) although no longitudinal study of serial measurements has been reported in children. A study was undertaken to determine whether the initial, final, or the rate of fall of forced expiratory volume in 1 second (FEV1) or peak VO2 was a better predictor of mortality...
متن کاملCYSTIC FIBROSIS Peak oxygen uptake and mortality in children with cystic fibrosis
Background: Single measurements of peak oxygen uptake (V̇O2) have been shown to predict mortality in patients with cystic fibrosis (CF) although no longitudinal study of serial measurements has been reported in children. A study was undertaken to determine whether the initial, final, or the rate of fall of forced expiratory volume in 1 second (FEV1) or peak V̇O2 was a better predictor of mortalit...
متن کاملPrevalence of Cystic Fibrosis Trans-membrane Conductance Regulator Gene common mutations in children with cystic fibrosis in Isfahan, Iran
Background: Cystic fibrosis (CF) is the most common lethal genetic disorder of Cystic Fibrosis Trans-membrane Conductance (CFTR) Regulator gene mutations. We aimed to investigate common mutations in CF patients and to assess its possible relationship with clinical presentations. Materials and Methods: This cross sectional study was conducted on 36 CF patients who were referred to a tertiary ped...
متن کاملCYSTIC FIBROSIS Airway remodelling in children with cystic fibrosis
Background: The relationship between airway structural changes and inflammation is unclear in early cystic fibrosis (CF) lung disease. A study was undertaken to determine changes in airway remodelling in children with CF compared with appropriate disease and healthy controls. Methods: Bronchoalveolar lavage and endobronchial biopsy were performed in a cross-sectional study of 43 children with C...
متن کاملValidity of the oxygen uptake efficiency slope in children with cystic fibrosis and mild-to-moderate airflow obstruction.
PURPOSE The oxygen uptake efficiency slope (OUES) has been proposed as an 'effort-independent' measure of cardiopulmonary exercise capacity, which could be used as an alternative measurement for peak oxygen uptake (VO(2peak)) in populations unable or unwilling to perform maximal exercise. The aim of the current study was to investigate the validity of the OUES in children with cystic fibrosis (...
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ژورنال
عنوان ژورنال: Thorax
سال: 2005
ISSN: 0040-6376
DOI: 10.1136/thx.2003.008102